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Telegraph.co.uk

Wednesday 04 April 2012

islet cell neoplasm vhl

Pancreatic Islet Cell Tumor Imaging
May 27, 2011 . Islet cell tumors may be functional or nonfunctional; although . Pancreatic islet cell tumors may secrete 2 or more polypeptide hormones.
http://emedicine.medscape.com/article/369655-overview

Pancreatic Islet Cell Tumors
describes the development of pancreatic islet cell tumors in fourof five female siblings. VHL mutation analysis was performed in an attempt to determine if .
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1191240/pdf/annsurg00012-0091.pdf

VHLFA: VHL in the Pancreas
There are three types of cysts and lesions which may be found commonly in the pancreas: cysts, serous microcystic adenomas, and islet cell tumors. Pancreatic .
http://www.vhl.org/profinfo/pancreas.php

High Frequency Loss of Heterozygosity in von Hippel-Lindau (VHL ...
Apr 1, 2002 . Progression to malignancy in VHL disease is associated primarily with the development of renal cell carcinoma (RCC) and pancreatic islet cell .
http://cancerres.aacrjournals.org/content/62/7/1952

Pancreas tumor - Discussion - VHL Family Alliance Support ...
Dec 5, 2008 . I have a small pancreas tumor that is described as an "islet cell . Sorry for the typo--I just lost my dad to VHL and I'm not thinking really clear .
https://www.inspire.com/groups/vhl-family-alliance/discussion/pancreas-tumor/

Center for Cancer Research - Staff Pages
Sep 21, 2011 . Germline mutations in the VHL gene predispose individuals to a variety of tumors , including renal carcinoma, CNS hemangioblastoma, islet cell .
http://ccr.cancer.gov/staff/staff.asp?profileid=5755

Deciphering von Hippel-Lindau (VHL/Vhl)-Associated Pancreatic ...
In addition, 12–17% of VHL patients develop pancreatic neuroendocrine (islet cell) tumors, which possess the malignant potential to develop metastasis [31], .
http://www.plosone.org/article/info:doi%2F10.1371%2Fjournal.pone.0004897

Endoscopic Treatment
Jun 3, 2011 . As a result, patients with an islet cell tumor / endocrine neoplasm have a . The pancreatic tumors in patients with VHL are interesting because .
http://pathology2.jhu.edu/pancreas/endocrineislet.cfm

VHLD/89211 Clinical: Von Hippel-Lindau (VHL) Deletion Detection
Von Hippel-Lindau (VHL) disease is an autosomal dominant cancer . cysts/ adenomas/carcinomas, islet cell tumors, and endolymphatic sac tumors can also .
http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/89211

Systematic comparison of sporadic and syndromic pancreatic islet cell
Table 1 von Hippel–Lindau disease (VHL) germline mutations in VHL patients with islet cell tumors (ICTs). Nucleotide change. Consequence. VHL patients .
http://erc.endocrinology-journals.org/content/17/4/875.full.pdf

Von Hippel-Lindau Disease Treatment, Hemangioblastomas ...
Oct 19, 2011 . Pancreatic islet cell tumors (can be malignant) and cystadenomas occur in VHL. Therefore, VHL patients should be followed regularly with .
http://www.brighamandwomens.org/Departments_and_Services/neurosurgery/Patient/VHLclinicFacts.aspx

Endocrine Pancreatic Cancer - definition of Endocrine Pancreatic ...
Von Hippel-Lindau (VHL) syndrome is another genetic disorder that causes multiple tumors, and 10-15% of VHL patients will develop islet cell cancer.
http://medical-dictionary.thefreedictionary.com/Endocrine+Pancreatic+Cancer

Title of Presentation
52 y.o. F w/ known VHL presents 5/99 s/p partial R . Renal cysts and RCC, pancreatic cysts and Islet cell tumors . Age- related probability of tumor in VHL .
http://eradiology.bidmc.harvard.edu/LearningLab/genito/Ryan.pdf

Role of VHL Gene Mutation in Human Cancer
Dec 15, 2004 . dolymphatic sac tumors of the inner ear, epididymal and broad ligament cystadeno- mas, and islet-cell tumors of the pancreas.5. VHL disease .
http://jco.ascopubs.org/content/22/24/4991.full.pdf

Use of the Tyrosine Kinase Inhibitor Sunitinib in a Patient with von ...
Patients with VHL are prone to develop different neuroendocrine and other neoplasms that are often highly vas- cularized, such as islet cell tumors, .
http://jcem.endojournals.org/content/94/2/386.full.pdf

von Hippel-Lindau Disease
VHL is associated with renal cell carcinoma (RCC), pheochromocytoma, heman- . islet cell tumors: evidence for stepwise mechanism for malignant conver- .
http://www.mhprofessional.com/downloads/products/0071606459/morita_ch23.pdf

Surgical decision-making affected by clinical and genetic screening ...
. novel kindred with von Hippel-Lindau disease and pancreatic islet cell tumors. . DATA: Patients with VHL disease have a propensity to develop neoplasms of .
http://www.ncbi.nlm.nih.gov/pubmed/9488521

Systematic comparison of sporadic and syndromic pancreatic islet cell
Oct 5, 2010 . Pancreatic islet cell tumors (ICTs) occur as sporadic neoplasias or . Systematic comparison of VHL-ICTs and sporadic ICTs has been lacking.
http://www.ncbi.nlm.nih.gov/pubmed/20660572

A clinical and scientific review - VHL Family Alliance
Mar 9, 2011 . haemangioblastomas, clear cell renal cell carcinoma (RCC), phaeo- chromocytoma, pancreatic islet tumours and endolymphatic sac tumours .
http://www.vhl.org/profinfo/Maher%20Neumann%20Richard.pdf

VHLFA: VHL Handbook v4, VHL in the Pancreas
What You Need to Know about VHL, VHL in the Pancreas. . cysts; serous microcystic adenomas, or “cystadenomas”; islet cell tumors, or pancreatic .
http://www.vhl.org/handbook/vhlhb2h.php

Linehan M.D. - CCR Clinical Trials at NIH - National Cancer Institute
Germline mutations in the VHL gene predispose individuals to a variety of tumors , including renal carcinoma, CNS hemangioblastoma, islet cell tumors of the .
http://bethesdatrials.cancer.gov/investigator-profiles/linehan/default.asp

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