Wednesday 04 April 2012

islet cell neoplasm vhl

Pancreatic Islet Cell Tumor Imaging
May 27, 2011 . Islet cell tumors may be functional or nonfunctional; although . Pancreatic islet cell tumors may secrete 2 or more polypeptide hormones.

Pancreatic Islet Cell Tumors
describes the development of pancreatic islet cell tumors in fourof five female siblings. VHL mutation analysis was performed in an attempt to determine if .

VHLFA: VHL in the Pancreas
There are three types of cysts and lesions which may be found commonly in the pancreas: cysts, serous microcystic adenomas, and islet cell tumors. Pancreatic .

High Frequency Loss of Heterozygosity in von Hippel-Lindau (VHL ...
Apr 1, 2002 . Progression to malignancy in VHL disease is associated primarily with the development of renal cell carcinoma (RCC) and pancreatic islet cell .

Pancreas tumor - Discussion - VHL Family Alliance Support ...
Dec 5, 2008 . I have a small pancreas tumor that is described as an "islet cell . Sorry for the typo--I just lost my dad to VHL and I'm not thinking really clear .

Center for Cancer Research - Staff Pages
Sep 21, 2011 . Germline mutations in the VHL gene predispose individuals to a variety of tumors , including renal carcinoma, CNS hemangioblastoma, islet cell .

Deciphering von Hippel-Lindau (VHL/Vhl)-Associated Pancreatic ...
In addition, 12–17% of VHL patients develop pancreatic neuroendocrine (islet cell) tumors, which possess the malignant potential to develop metastasis [31], .

Endoscopic Treatment
Jun 3, 2011 . As a result, patients with an islet cell tumor / endocrine neoplasm have a . The pancreatic tumors in patients with VHL are interesting because .

VHLD/89211 Clinical: Von Hippel-Lindau (VHL) Deletion Detection
Von Hippel-Lindau (VHL) disease is an autosomal dominant cancer . cysts/ adenomas/carcinomas, islet cell tumors, and endolymphatic sac tumors can also .

Systematic comparison of sporadic and syndromic pancreatic islet cell
Table 1 von Hippel–Lindau disease (VHL) germline mutations in VHL patients with islet cell tumors (ICTs). Nucleotide change. Consequence. VHL patients .

Von Hippel-Lindau Disease Treatment, Hemangioblastomas ...
Oct 19, 2011 . Pancreatic islet cell tumors (can be malignant) and cystadenomas occur in VHL. Therefore, VHL patients should be followed regularly with .

Endocrine Pancreatic Cancer - definition of Endocrine Pancreatic ...
Von Hippel-Lindau (VHL) syndrome is another genetic disorder that causes multiple tumors, and 10-15% of VHL patients will develop islet cell cancer.

Title of Presentation
52 y.o. F w/ known VHL presents 5/99 s/p partial R . Renal cysts and RCC, pancreatic cysts and Islet cell tumors . Age- related probability of tumor in VHL .

Role of VHL Gene Mutation in Human Cancer
Dec 15, 2004 . dolymphatic sac tumors of the inner ear, epididymal and broad ligament cystadeno- mas, and islet-cell tumors of the pancreas.5. VHL disease .

Use of the Tyrosine Kinase Inhibitor Sunitinib in a Patient with von ...
Patients with VHL are prone to develop different neuroendocrine and other neoplasms that are often highly vas- cularized, such as islet cell tumors, .

von Hippel-Lindau Disease
VHL is associated with renal cell carcinoma (RCC), pheochromocytoma, heman- . islet cell tumors: evidence for stepwise mechanism for malignant conver- .

Surgical decision-making affected by clinical and genetic screening ...
. novel kindred with von Hippel-Lindau disease and pancreatic islet cell tumors. . DATA: Patients with VHL disease have a propensity to develop neoplasms of .

Systematic comparison of sporadic and syndromic pancreatic islet cell
Oct 5, 2010 . Pancreatic islet cell tumors (ICTs) occur as sporadic neoplasias or . Systematic comparison of VHL-ICTs and sporadic ICTs has been lacking.

A clinical and scientific review - VHL Family Alliance
Mar 9, 2011 . haemangioblastomas, clear cell renal cell carcinoma (RCC), phaeo- chromocytoma, pancreatic islet tumours and endolymphatic sac tumours .

VHLFA: VHL Handbook v4, VHL in the Pancreas
What You Need to Know about VHL, VHL in the Pancreas. . cysts; serous microcystic adenomas, or “cystadenomas”; islet cell tumors, or pancreatic .

Linehan M.D. - CCR Clinical Trials at NIH - National Cancer Institute
Germline mutations in the VHL gene predispose individuals to a variety of tumors , including renal carcinoma, CNS hemangioblastoma, islet cell tumors of the .

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